Creation
Inarius + Lilith steal the Worldstone and create Sanctuary — a hidden realm outside the Eternal Conflict. The Nephalem are born.
~1,000 yrs before D1
Horadrim order formed by Tyrael. Mages hunt the Prime Evils across Sanctuary, imprisoning them in Soulstones.
~200 yrs before D1
The Dark Exile — Lesser Evils overthrow and banish the Prime Evils to the mortal realm.
Diablo 1 (1265)
Diablo possesses King Leoric, then the hero of Tristram. The hero drives the Soulstone into their own skull to contain him.
Diablo 2 (1265)
The wanderer (corrupted D1 hero) frees Baal. Heroes chase Diablo through Sanctuary, defeat Mephisto and Diablo. Then face Baal at Mount Arreat.
D2: LoD Ending
Baal corrupts the Worldstone. Tyrael destroys it — the explosion reshapes the world. Tyrael goes missing.
Diablo Immortal (1270)
Set between D2 and D3. Heroes hunt Worldstone shards across Sanctuary. New demon lords emerge.
Diablo 3 (1285)
Tyrael falls as a mortal star into Tristram Cathedral. Leah (daughter of Adria + the D1 hero) is possessed by Diablo. The Ultimate Evil storms the High Heavens.
D3: Reaper of Souls
Malthael — former Archangel of Wisdom — becomes the Angel of Death. Absorbs the Black Soulstone. Threatens all life. Defeated by the Nephalem.
Diablo 4 (1336)
Lilith is summoned back to Sanctuary by blood ritual. Seeks to make humanity powerful enough to resist both Heaven and Hell. Inarius returns. Both are defeated.
D4: Vessel of Hatred
Neyrelle carries Mephisto in the Black Soulstone to Nahantu. Mephisto manipulates and escapes. The story continues.